Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus.

We describe a collaborative study to investigate the comparability of serologic assays for MERS-CoV and assess any benefit associated with the introduction of a standard reference reagent for MERS-CoV serology. Our study findings indicate that, when possible, laboratories should use a testing algorithm including >2 tests to ensure correct diagnosis of MERS-CoV. We also demonstrate that the use of a reference reagent greatly improves the agreement between assays, enabling more consistent and therefore more meaningful comparisons between results.
PMID: 31423969 [PubMed - as supplied by publisher]

Source: Emerging Infectious Diseases - August 20, 2019 Category: Infectious Diseases Authors: Harvey R, Mattiuzzo G, Hassall M, Sieberg A, Müller MA, Drosten C, Rigsby P, Oxenford CJ, study participants Tags: Emerg Infect Dis Source Type: research