Engineering "cell-particle hybrids" of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation.

This study presents a promising platform that facilitates the translation of local immunomodulation towards an effective strategy with improved safety profiles for treating type I diabetes.
PMID: 31419652 [PubMed - as supplied by publisher]

Source: Biomaterials - August 5, 2019 Category: Materials Science Authors: Nguyen TT, Pham TT, Nguyen HT, Nepal MR, Phung CD, You Z, Katila N, Pun NT, Jeong TC, Choi DY, Park PH, Yong CS, Kim JO, Yook S, Jeong JH Tags: Biomaterials Source Type: research