Diagnostic accuracy of 16S rDNA PCR in bacterial pyomyositis: a prospective study

In this Journal, Lelouvier and colleagues reported the use of 16S metagenomic sequencing to diagnose polymicrobial and culture-negative bacteraemia.1 We also used 16S rDNA PCR to study the bacteriology of bacterial pyomyositis, a rare infection of skeletal muscles in which cultures are often sterile as most patients are receiving antibiotic therapy for days or even weeks prior to aspiration of pus.2 Indeed, establishing the diagnosis is a clinical challenge as initial symptoms are nonspecific and last for a mean duration of 23 days before hospitalization.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research