Small Molecules-Peptides for Neuroscience Research

Agonists, Antagonists, Inhibitors and Ligands for Studying NeuromodulationOur friends at R and D Systems/Tocris Bioscience have made available to us select Small Molecules/Peptides. Our focus will be on providing agonists, antagonists, inhibitors and ligands that complement our Neuroscience and Pain Research products and expertise.2-APB=TRP Channel ModulatorWe will be adding about 10 new molecules/peptides per month. Here's a sampling our our most recent additions:NameTypeBioactivity(±)-trans-ACPDAgonistPotent NMDA agonist. Also group II mGluR agonist(S)-(-)-5-FluorowillardiineAgonistVery potent AMPA agonist(S)-4-CarboxyphenylglycineAntagonistCompetitive group I mGluR antagonist/weak group II agonist2-APBModulatorTRP channel modulator. Also IP3 receptor antagonist2-Methylthioadenosine triphosphate tetrasodium saltAgonistP2 purinergic agonistAM 404ModulatorVanilloid receptor agonist. Also anandamide transport inhibitorBRL 52537 hydrochlorideLigandPotent and selective κ opioid receptor agonistCNQXAntagonistPotent AMPA/kainate antagonistClocinnamox mesylateAntagonistIrreversible μ-opioid receptor antagonistEndomorphin-1AgonistPotent and selective μ opioid receptor agonistEndomorphin-2AgonistPotent and selective μ opioid receptor agonistFITAgonistIrreversible δ opioid receptor agonistGBR 13069 dihydrochlorideAgonistPotent dopamine uptake inhibitorL-NIO dihydrochlorideInhibitorPotent eNOS inhibitorL-Quisqualic acidAgonis...

Source: Neuromics - April 22, 2013 Category: Neuroscience Tags: agonist Mu Opioid Receptor Neuromodulation P2X3 Synaptic Plasticity ligands antagonists Opioid Receptors neuroscience inhibitors TRPV1 logands Nociception Neurotransmission Source Type: news