Antibodies in Repeated Influenza Vaccination (ARIVA) Study

Condition:   Vaccine Response Impaired Intervention:   Biological: Influenza Vaccination Sponsors:   University Hospital, Basel, Switzerland;   University of Oslo;   University of Oxford;   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Abstract SUMMARYPatients undergoing solid-organ transplantation (SOT) or allogeneic hematopoietic cell transplantation (HCT) are at increased risk for infectious complications. Community-acquired respiratory viruses (CARVs) pose a particular challenge due to the frequent exposure pre-, peri-, and posttransplantation. Although influenza A and B viruses have a top priority regarding prevention and treatment, recent molecular diagnostic tests detecting an array of other CARVs in real time have dramatically expanded our knowledge about the epidemiology, diversity, and impact of CARV infections in the general populatio...
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
Early Childhood Education Centre (ECEC) staff are strongly recommended to receive several immunizations including influenza and pertussis. However, evidence regarding the uptake is either old or lacking across...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
This study aims to characterize attitudes and knowledge towards immunization practice of people aged>65 years for seasonal influenza (SIV), pneumococcus (PNV), and Herpes zoster (ZV) in a sample of Italian general practitioners (GPs). MATERIALS AND METHODS: During 10/2018, a structured questionnaire was emailed to 274 GPs operating in the Province of Parma, Italy. Association between willingness to perform aforementioned vaccines and individual factors was assessed through a multivariate regression analysis by calculating multivariate Odds Ratio (mOR). RESULTS: A total of 73 GPs (26.6% of original sample) comp...
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research
CONCLUSIONS: This analysis confirms the importance of the virological surveillance and highlights the need of a continuous monitoring of IVs circulation, to improve the most appropriate vaccination strategies. (www.actabiomedica.it). PMID: 31517888 [PubMed - in process]
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research
CONCLUSIONS: The possibility to make accurate and continuous VE estimates during the season will help to better define the composition of the vaccine for the following season. PMID: 31517886 [PubMed - in process]
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research
A September pediatric flu death in California serves as a stark reminder that getting vaccinated early can save lives. Public-health officials in Riverside County, Calif. announced this week that a recently deceased 4-year-old child from Perris, who had underlying health issues, tested positive for influenza. The case is the county’s first pediatric flu-related death of the 2019-2020 flu season, according to a release. (The spread of flu typically picks up in October or November, and can last until May.) While it may feel too early to think about the flu, the U.S. Centers for Disease Control and Prevention (CDC) said...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized flue season public health Source Type: news
by Alexander D. Becker, Amy Wesolowski, Ottar N. Bj ørnstad, Bryan T. Grenfell A key question in ecology is the relative impact of internal nonlinear dynamics and external perturbations on the long-term trajectories of natural systems. Measles has been analyzed extensively as a paradigm for consumer-resource dynamics due to the oscillatory nature of the host-pathogen life cy cle, the abundance of rich data to test theory, and public health relevance. The dynamics of measles in London, in particular, has acted as a prototypical test bed for such analysis using incidence data from the pre-vaccination era (1944–...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
CONCLUSIONS: Influenza and pneumococcus vaccinations are effective and safe in patients with ARDs. More efforts should be made to translate the accumulated evidence into practice. PMID: 31498077 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Conditions:   Asthma in Children;   Influenza Vaccine;   Immunization Coverage Intervention:   Sponsor:   Central Hospital, Nancy, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: October 2019Source: Molecular Immunology, Volume 114Author(s): Aritraa Lahiri, Shayan Sharif, Amirul Islam MallickAbstractCompounding with the problem of frequent antigenic shift and occasional drift of the segmented genome of Avian Influenza Virus (AIV), vaccines based on major surface glycoproteins such as haemagglutinin (HA) to counter heterosubtypic AIV infection in chickens remain unsuccessful. In contrast, neuraminidase (NA), the second most abundant surface glycoprotein present in viral capsid is less mutable and, in some instances, successful in eliciting inter-species cross-reactive antibody resp...
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
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