Cancers, Vol. 11, Pages 1180: Third Epidemiological Analysis of Nasopharyngeal Carcinoma in the Central Region of Japan from 2006 to 2015

This study was designed in line with to two previous clinical studies into NPC conducted in the same area of Japan. We recruited NPC patients diagnosed in hospitals across this area over a 10-year period (2006–2015) using a questionnaire about sex, age, primary site, clinical symptoms, pathology, Union for International Cancer Control (UICC) staging, serological exam, treatment, and survival. A total of 620 NPC patients were identified. The age-standardized incidence of NPC from 2006 to 2015 was 0.27 per 100,000 individuals per year. There were no significant differences between this study and the previous two studies conducted in the same area of Japan. The five-year overall survival rate for all patients was 75.9%, while those for patients with stages I, II, III, and IVA were 97%, 91%, 79%, and 68%, respectively. The age-standardized annual incidence of NPC in the present study was 0.27 per 100,000 individuals per year, which was relatively low and stable. The five-year overall survival rate for all NPC patients was significantly improved in this decade compared with previous studies. The smoking rates in male and female NPC patients were 64.5% and 18.8%, respectively, thereby suggesting the involvement of smoking in the incidence of NPC.

Source: Cancers - August 14, 2019 Category: Cancer & Oncology Authors: Masafumi Kanno Norihiko Narita Yasushi Fujimoto Naohiro Wakisaka Tomokazu Yoshizaki Takeshi Kodaira Chiyoko Makita Yuichiro Sato Keisuke Yamazaki Takanori Wakaoka Yuzo Shimode Hiroyuki Tsuji Ryosuke Kito Hajime Ishinaga Seiji Hosokawa Hiromasa Takakura Ku Tags: Article Source Type: research