Small molecule HDAC inhibitors: Promising agents for breast cancer treatment.

In conclusion, HDACIs have shown desirable effects on breast cancer, especially when they are used in combination with other anticancer agents. In the coming future, more multicenter and randomized Phase III studies are expected to be conducted pushing promising new therapies closer to the market. In addition, the design and synthesis of novel HDACIs are also needed.
PMID: 31408831 [PubMed - as supplied by publisher]

Source: Bioorganic Chemistry - August 4, 2019 Category: Chemistry Authors: Huang M, Zhang J, Yan C, Li X, Zhang J, Ling R Tags: Bioorg Chem Source Type: research