Healthy living could prevent a THIRD of dementia cases, expert says 

Professor Alistair Burns, the national clinical lead for dementia in the NHS, said up to a third of cases were potentially preventable as they were linked to diet, inactivity or poor brain health.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Dear Candid Caregiver: My mom passed two years ago and my dad hasn’t done well since. Recently he had a stroke. My sister, who lives 1,000 miles away, came out for mom’s funeral, and she also visited for a few days after dad’s stroke, but she has a job and a family and couldn’t stay long. Now, dad’s been diagnosed with vascular dementia. Realistically, I’m the sole caregiver. I have two teenaged children, a husband who is, so far, supportive, and a job. I’m already beginning to feel burned out after just a few months.  Read the full article on HealthCentral to learn more ...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
CONCLUSIONS: This study highlights that the proportion of older adults hospitalised for a medication misadventure is much higher among those with dementia, than those without dementia. Strategies should target older adults, and especially those with dementia, to reduce medication-related harm and improve patient safety. PMID: 31353769 [PubMed - as supplied by publisher]
Source: Australasian Journal on Ageing - Category: Geriatrics Authors: Tags: Australas J Ageing Source Type: research
Dear Candid Caregiver: My mom passed two years ago and my dad hasn’t done well since. Recently he had a stroke. My sister, who lives 1,000 miles away, came out for mom’s funeral, and she also visited for a few days after dad’s stroke, but she has a job and a family and couldn’t stay long. Now, dad’s been diagnosed with vascular dementia. Realistically, I’m the sole caregiver. I have two teenaged children, a husband who is, so far, supportive, and a job. I’m already beginning to feel burned out after just a few months. What can I do to help myself get through this and still take car...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Conclusion: Using a largely theoretical model, the six modifiable lifestyle factors were estimated to be attributable to 50.9% of dementia cases in Barbados. Since the risk factors have much in common, any intervention that targets one of them could significantly reduce future dementia prevalence. PMID: 31093046 [PubMed]
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
In this study, we report the age-associated differences between fetal MSC (fMSC) populations and MSCs isolated from elderly donors with respect to their transcriptomes. We successfully reprogrammed fMSCs (55 days post conception) and adult MSC (aMSC; 60-74 years) to iPSCs and, subsequently, generated the corresponding iMSCs. In addition, iMSCs were also derived from ESCs. The iMSCs were similar although not identical to primary MSCs. We unraveled a putative rejuvenation and aging gene expression signature. We show that iMSCs irrespective of donor age and cell type re-acquired a similar secretome to that of th...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease Tracy R. Melzer1,2,3†, Megan R. Stark1,2†, Ross J. Keenan1,4, Daniel J. Myall1, Michael R. MacAskill1,2, Toni L. Pitcher1,2,3, Leslie Livingston1,2, Sophie Grenfell1, Kyla-Louise Horne1,2, Bob N. Young1, Maddie J. Pascoe1, Mustafa M. Almuqbel1,2,4, Jian Wang5, Steven H. Marsh6, David H. Miller1,2,7, John C. Dalrymple-Alford1,2,3,8 and Tim J. Anderson1,2,3,9* 1New Zealand Brain Research Institute, Christchurch, New Zealand 2Department of Medicine, University of Otago, Christchurch, New Zealand 3Brain Rese...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Photo credit Claudia Soraya Dear Carol: My mother developed vascular dementia, personality issues, and speech problems after a stroke three years ago. She lives with me, and because of her difficult personality, my daughter no longer wants to bring my grandchildren here to visit. I retired early to care for Mom but now I feel trapped. Nothing I do for her is right. I’ve suggested that she might have a better life if she moved to assisted living and, surprisingly, she isn’t resistant though I know she’ll complain about them, too, if she moves. My sisters live out of the area so they are limi...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Grand Total EEG Score Can Differentiate Parkinson's Disease From Parkinson-Related Disorders Ela Austria Barcelon1,2*, Takahiko Mukaino1, Jun Yokoyama1, Taira Uehara2, Katsuya Ogata2, Jun-ichi Kira1 and Shozo Tobimatsu2 1Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan2Department of Clinical Neurophysiology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Background: Semi-quantitative electroencephalogram (EEG) analysis is easy to perform and has been used to differentiate dementias, as well ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
François Chassagne1†, Xinyi Huang1†, James T. Lyles1 and Cassandra L. Quave1,2* 1Center for the Study of Human Health, Emory University, Atlanta, GA, United States 2Department of Dermatology, Emory University, Atlanta, GA, United States In the search for new therapeutic solutions to address an increasing number of multidrug-resistant bacterial pathogens, secondary metabolites from plants have proven to be a rich source of antimicrobial compounds. Ginkgo biloba, a tree native to China, has been spread around the world as an ornamental tree. Its seeds have been used as snacks and medical mater...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion: Reduced saliva SP concentrations may predict early pharyngeal swallowing dysfunction in PD patients. This finding supports the hypothesis that an impaired SP mediated neurotransmission has a significant impact for the development of dysphagia in PD patients. Larger studies are needed to confirm SP as a clinical useful biomarker for early detection of PD-related dysphagia. Introduction Following Alzheimer's disease, Parkinson's disease (PD) is the second most common neurodegenerative disorder (1, 2). Oropharyngeal dysphagia is a clinically relevant symptom in affected patients as the majori...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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