Therapeutic Effects of Hyaluronic Acid in Bacterial Pneumonia in the Ex Vivo Perfused Human Lungs.

Conclusions: EVs induced and released during severe bacterial pneumonia were inflammatory and induced ALI, and HMW HA administration was effective in inhibiting the uptake of EVs by target cells and decreasing lung injury from E.coli EVs or bacterial pneumonia.
PMID: 31390880 [PubMed - as supplied by publisher]

Source: American Journal of Respiratory and Critical Care Medicine - August 6, 2019 Category: Respiratory Medicine Authors: Liu A, Park JH, Zhang X, Sugita S, Naito Y, Lee JH, Kato H, Hao Q, Matthay MA, Lee JW Tags: Am J Respir Crit Care Med Source Type: research