Increased depression-related behavior during the postpartum period in inbred BALB/c and C57BL/6 strains

Pregnancy and lactation are characterized by dramatic changes in the endocrine system and brain in mammalian females. These changes, with stress before pregnancy, are potential risk factors for the development...
Source: Molecular Brain - Category: Neuroscience Authors: Tags: Research Source Type: research

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In this study we examined the extent to which postnatal bonding, maternal mental health, and substance use at 8-weeks postpartum predicted mother –infant bonding (self-report) and mother emotional availability (observational) at 12-months of age.MethodsData were obtained from an Australian longitudinal cohort study of pregnancy (n  = 308). Data were collected during pregnancy, at birth, and postnatally at 8-weeks and 12-months.ResultsThe results show strong continuity between postnatal bonding at 8-weeks and 12-months. Early postpartum stress and depression were associated with bonding at 12-months; how...
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
Authors: Gordon H, Nath S, Trevillion K, Moran P, Pawlby S, Newman L, Howard LM, Molyneaux E Abstract OBJECTIVE: To investigate the association between maternal self-harm (lifetime history of self-harm and self-harm ideation during pregnancy) and mother-infant interactions in a representative cohort from southeast London. METHODS: Data were drawn from a prospective cohort of 545 women attending antenatal appointments between 2014 and 2016. Women were asked about history of self-harm and current self-harm ideation during a research interview following first antenatal visit. Follow-up data on depressive symptoms ...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Astudy inAJP in Advance provides further evidence that the detrimental effects of adverse life experiences can carry across generations. Researchers found that children of mothers who experienced stressful events during childhood had greater biological signs of stress and were more likely to have behavioral problems at 18 months.“[O]ur data, when combined with findings from other studies, confirm maternal life-course experiences as a potent predictor of offspring mental and physical well-being,” wrote Kyle Esteves, M.P.H., of Tulane University School of Medicine and colleagues. “Our results suggest that s...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance anxiety depression early life adversity externalizing problems generational effects internalizing problems Kyle Esteves mental health pregnant women telomeres Source Type: research
Publication date: Available online 11 September 2019Source: Reproductive BioMedicine OnlineAuthor(s): Jingwen Lang, Bingqian Zhang, Yueru Meng, Yanzhi Du, Linlin Cui, Weiping LiABSTRACTResearch QuestionAre maternal depression and anxiety disorders (MDAD) before and during pregnancy associated with in vitro fertilization (IVF) outcomes?DesignA total of 5556 women with their first IVF cycle started between August 15th, 2014, and December 31st, 2015 were pooled from a prospective cohort of assisted reproductive technology (ART) children. The self-rating depression scale (SDS) and self-rating anxiety scale (SAS) were used to d...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
[Nigeria Health Watch] "I felt thoroughly inadequate. I didn't feel like I was attractive enough. I didn't feel like I was doing enough. Nobody told me I could feel that way"  -- Patience, Post Partum Depression Survivor
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
Publication date: Available online 8 September 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Andrée-Anne Hudon Thibeault, Yossef López de Los Santos, Nicolas Doucet, J. Thomas Sanderson, Cathy VaillancourtAbstractSerotonin reuptake inhibitors (SRIs) are currently the main molecules prescribed to pregnant women that suffer from depression. Placental cells are exposed to SRIs via maternal blood, and we have previously shown that SRIs alter feto-placental steroidogenesis in an in vitro co-culture model. More specifically, serotonin (5-HT) regulates the estrogen biosynthetic enzy...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
CONCLUSION: Though absolute numbers were modest, severe maternal morbidity was associated with increased risk of severe postpartum psychiatric morbidity and substance use disorder. The highest period of risk extended to 4 months after hospital discharge. PMID: 31503165 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
CONCLUSION: Pregnancy offered a pivotal opportunity for homeless women to engage with care for their complex needs and improve self-care, despite mistrust of practitioners. Poor postnatal support and the distress of CLSS reinforced an ongoing cycle of grief, mental health crises, substance use relapse, and homelessness. PMID: 31501164 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - Category: Primary Care Authors: Tags: Br J Gen Pract Source Type: research
This study investigated potential associations between exposure to prenatal stress and personality disorder in offspring. METHOD: In a subsample (N = 3626) of a large Finnish birth cohort, we used logistic regression models to examine associations between self-reported maternal stress during pregnancy, collected monthly during antenatal clinic appointments, and personality disorder in offspring. Familial and outcome information were obtained by linking data from the Finnish Hospital Discharge Register and the Finnish Population Register. RESULTS: Compared with those unexposed, children exposed to any maternal stres...
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Background andObjectives: During pregnancy and the postnatal period many changes occur in a woman's body, both in mental and physical spheres. The birth of a child and a new role-of a mother-can sometimes be associated with numerous ne...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
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