Adherence to EAU guidelines on penile cancer translates into better outcomes: a multicenter international study

ConclusionsOur findings suggest that there is a good adherence to the EAU GL on PC. However, this should be further reinforced, endorsed and encouraged as it might translate into better clinical outcomes for PC patients.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research

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Publication date: 2019Source: European Urology Supplements, Volume 18, Issue 5Author(s): A.L. Walsh, N.A. Abdullah, P. Ahern, P. Sweeney
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research
Quality of life transplantations (e.g. hand, face, etc.), in contrast to life-saving transplantations (e.g. heart, lungs, etc.), have become increasingly popular and have gained more acceptance in the medical and lay communities. In the last two decades transplants for sexual and reproductive organs—specifically allogenic transplantations of the uterus, ovary, and penis—have emerged as yet another type of quality of life transplants. The purpose of uterus transplantations is to allow cisgender women with absolute uterine factor infertility to experience pregnancy. Although the first uterus transplantation took ...
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care assisted reproduction feminist ethics reproductive medicine Sex and Sexuality surgical ethics syndicated transplantation Women's Reproductive Rights Source Type: blogs
Most men and women did not know anal, penile, and oral cancers are caused by HPV
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Infections, Internal Medicine, Nursing, Oncology, Pediatrics, Pharmacy, Journal, Source Type: news
Testicular cancer occurs in the testicles , which are located inside the scrotum, a loose bag of skin underneath the penis. The cancer tends to mostly affect men between 15 and 49 years of age. Testicular cancer is highly treatable, even when cancer has spread beyond the testicle. Testicular cancer that has spread to other parts of the body may reveal itself in a number of ways.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 13 September 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Andreas KortenkampAbstractThere is concern about cumulative exposures to compounds that disrupt male sexual differentiation in foetal life, leading to irreversible effects in adulthood, including declines in semen quality, testes non-descent, malformations of the penis and testis cancer. Traditional chemical-by-chemical risk assessment approaches cannot capture the likely cumulative health risks. Past efforts of focusing on combinations of phthalates, a subgroup of chemicals suspected of contributing to these risks, d...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Authors: Zeuschner P, Linxweiler J, Junker K Abstract Introduction: Non-coding RNAs (ncRNAs) are important regulators of cellular signaling in tumor-related processes. They can not only be detected in tumor tissues, but also in body fluids. ncRNAs are released into circulation as cell-free RNAs in at least two ways: bound to proteins like Ago2 or packed in extracellular vesicles (EV). Therefore, they have a great potential to serve as biomarkers in liquid biopsies. This review gives an overview of the current knowledge concerning ncRNAs and EVs as putative liquid biomarkers in urological tumor diseases. Areas cover...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
Publication date: Available online 4 September 2019Source: Urology Case ReportsAuthor(s): Cam Nguyen, Stephen Leslie, John Gross, Nicholas Dietz, Subodh M. Lele, Gopi SirineniAbstractPenile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
Abstract Human papilloma virus (HPV) affects predominantly the genital area, which includes vagina, cervix, penis, vulva scrotum, rectum and anus. Among 100 types of HPV, 14 types are considered to cause the risky cancer. The gene HPV-16 E7 is responsible for the development of cancer with the infected women. Earlier identification of this gene sequence avoids the cancer progression. The targeted HPV-16 E7 sequence was sandwiched by capture and reporter sequences on the carbodiimidazole-modified interdigitated electrode (IDE) surface. Target sequence at 100 fM was paired to the capture sequence immobilized on IDE ...
Source: International Journal of Biological Macromolecules - Category: Biochemistry Authors: Tags: Int J Biol Macromol Source Type: research
Conclusions In our study, the previously developed nomogram that was applied to our population had low accuracy and low precision for correctly identifying patients with PC who have positive ILNs.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusions In our study, the previously developed nomogram that was applied to our population had low accuracy and low precision for correctly identifying patients with PC who have positive ILNs.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
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