Age-dependent diagnostic accuracy of clinical scoring systems and D-dimer levels in the diagnosis of pulmonary embolism with computed tomography pulmonary angiography (CTPA)

ConclusionD-dimer measurement and clinical scores perform best in patients<  50 years. The YEARS score performs best across all age groups and is therefore recommended.Key Points• The probability of pulmonary embolism predicted by fibrin fibrinogen degradation products and clinical scores shows the highest accuracy in patients<  50 years.• The probability of pulmonary embolism predicted by the YEARS score shows the highest accuracy in each age group.• Classic Wells score and fibrin fibrinogen degradation products show a significant interaction with patient age in a logistic regression model.
Source: European Radiology - Category: Radiology Source Type: research