The Neutrophil to Lymphocyte Ratio Predicts the Response to Neoadjuvant Chemotherapy in Luminal B Breast Cancer.

CONCLUSIONS: HER2-enriched tumors had a higher probability of pCR. In Luminal<br />B tumors, NLR had a statistically significant relationship with the probability of pCR. In this subtype, NLR could be<br />a useful biomarker to predict tumor response to NAC. Further studies including other clinical parameters for systemic<br />inflammation such as platelet counts, intratumoral NLR or body mass index could help identify patients that would<br />get the most benefit from NAC. PMID: 31350986 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research