Reply

We thank Maggiore et  al for their thoughtful commentary regarding our article discussing corticosteroid therapy for children with indeterminate acute hepatitis and acute liver failure. We have read with interest their article describing the spectrum of disorders seen in children with what they labeled “seronegative autoimmune hepatitis.”1 This descriptive term was used for convenience, and in their letter the authors state that the children with hepatitis, normal IgG levels, and blood cytopenia or aplastic anemia had features more consistent with immune activation and dysregulation.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Letter to the Editor Source Type: research