Overcoming Tamoxifen Resistance by Regulation of Del-1 in Breast Cancer.

CONCLUSIONS: TAM-R breast cancer is characterized by Del-1 overexpression and tumor progression can be inhibited by Del-1 depletion, which restores TAM sensitivity. Thus, therapeutic strategies that target Del-1 may be effective for the treatment of hormone-resistant breast cancer.
PMID: 31330520 [PubMed - as supplied by publisher]

Source: Oncology - July 21, 2019 Category: Cancer & Oncology Authors: Lee J, Jeong JH, Jung JH, Kim WW, Lee SJ, Park JY, Park JY, Kang SH, Kim EA, Park JH, Chae YS, Park HY Tags: Oncology Source Type: research