Nerve growth factor (NGF): a potential urinary biomarker for overactive bladder syndrome (OAB)?

Conclusions
Whilst the evidence for an increased urinary NGF in OAB appears convincing, many questions about its validity remain including: specificity, sensitivity, cost‐ and time‐effectiveness.
Many criteria for what constitutes a biomarker still need to be evaluated and met before this molecule can be considered for this role.

Source: BJU International - February 27, 2013 Category: Urology & Nephrology Authors: Jai H. Seth, Arun Sahai, Mohammad S. Khan, Frank van der Aa, Dirk de Ridder, Jalesh N. Panicker, Prokar Dasgupta, Clare J. Fowler Tags: Review Source Type: research