Follow-up of active Aβ immunization in Alzheimer disease

Nature Reviews Neurology, Published online: 15 July 2019; doi:10.1038/s41582-019-0239-4A new report presents post-mortem neuropathological follow-up of patients 4 months to 15 years after they received active amyloid-β (Aβ) immunization during its first trial in Alzheimer disease. The study documents effects on plaque clearance, tau pathology, plasma anti-Aβ antibody titres and final cognitive status; variability was seen between patients.
Source: Nature Reviews Neurology - Category: Neurology Authors: Source Type: research