Comprehensive mismatch repair gene panel identifies variants in patients with Lynch ‐like syndrome

ConclusionWe have shown that other genes associated with the process of DNA MMR have a high probability of being associated with LLS families. These findings indicate that the spectrum of genes that should be tested when considering an entity like Lynch ‐like syndrome should be expanded so that a more inclusive definition of this entity can be developed.

https://onlinelibrary.wiley.com/doi/abs/10.1002/mgg3.850?af=R

Source: Molecular Genetics & Genomic Medicine - July 11, 2019 Category: Genetics & Stem Cells Authors: Alexandre Xavier, Maren Fridtjofsen Olsen, Liss A. Lavik, Jostein Johansen, Ashish Kumar Singh, Wenche Sjursen, Rodney J. Scott, Bente A. Talseth ‐Palmer Tags: ORIGINAL ARTICLE Source Type: research