Sleep deprivation and Modafinil affect cortical sources of resting state electroencephalographic rhythms in healthy young adults.

CONCLUSIONS: The present results suggest that posterior delta and alpha source activities may be both related to the regulation of human brain arousal and vigilance in quiet wakefulness.
SIGNIFICANCE: Future research in healthy young adults may use this methodology to preselect new symptomatic drug candidates designed to normalize brain arousal and vigilance in seniors with dementia.
PMID: 31295717 [PubMed - as supplied by publisher]

Source: Clinical Neurophysiology - June 30, 2019 Category: Neurology Authors: Del Percio C, Derambure P, Noce G, Lizio R, Faz DB, Blin O, Payoux P, Deplanque D, Méligne D, Chauveau N, Bourriez JL, Casse-Perrot C, Lanteaume L, Thalamas C, Dukart J, Ferri R, Pascarelli MT, Richardson JC, Bordet R, Babiloni C, PharmaCog Consortium Tags: Clin Neurophysiol Source Type: research