Silymarin Enriched Extract (Silybum marianum) Additive Effect on Doxorubicin-Mediated Cytotoxicity in PC-3 Prostate Cancer Cells

In conclusion, the DXR-SEE co-treatment provokes perturbations in the autophagic mechanism of prostate cancer cells (PC-3) compared to DXR treatment alone, causing an excessive cell death. These findings propose the putative use of SEE as an adjuvant cytotoxic agent. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Planta Medica - July 8, 2019 Category: Drugs & Pharmacology Authors: Gioti, Katerina Papachristodoulou, Anastasia Benaki, Dimitra Havaki, Sophia Beloukas, Apostolos Vontzalidou, Argyro Aligiannis, Nektarios Skaltsounis, Alexios-Leandros Mikros, Emmanuel Tenta, Roxane Tags: Original Papers Source Type: research