Investigation of arterial –cardiac–pulmonary interaction

This study investigated 55 consecutive subjects not suffering from pulmonary, vascular and cardiac disease who underwent health screening test at our medical center. First, the presence of atherosclerotic disease (hypertension, dyslipidemia and diabetes) and smoking status of the patients were determined. Next, pulmonary function test, vascular function test including cardio-ankle vascular index, and echocardiography were performed. Then, we examined the correlation among the pulm onary, vascular and the heart. Our results revealed many correlations among these three factors. Especially left atrial dimension (LAD) andE/A ratio (E/A) were important cardiac factors associated with both pulmonary and vascular functions independently. Conventionally, inflammatory responses are known to involve in the correlation between pulmonary and vascular functions. Our study demonstrated that cardiac function and morphology were also involved in this correlation, signifying that LAD andE/A plays important roles in the arterial –cardiac–pulmonary interaction.
Source: Heart and Vessels - Category: Cardiology Source Type: research