Potential To Prevent And Treat Alzheimer's Disease Offered By Novel Herbal Compound

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease. These results, which may shed light on the neuropathology of AD and open up new avenues of treatment, are available in the current issue of Restorative Neurology and Neuroscience...
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news

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Early-onset Alzheimer's disease (EOAD), defined as onset of AD before the age of 65  years, is less common than the late-onset type, and little is known about the factors affecting disease progression. The aim of the study was to investigate factors influencing disease progression in people with EOAD.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Original Study - Brief Report Source Type: research
The common neurodegenerative conditions are associated with various different forms of protein aggregation; a few proteins in the body have toxic alternative forms that can spread and cause harm to cells. Alzheimer's disease is associated with amyloid-β and tau, Parkinson's disease with α-synuclein, and so forth. But the decay of the aging brain is not a nice neat process in which one individual exhibits one clear-cut pathology with clear-cut symptoms indicative of that pathology. All protein aggregates occur in every aged person to some degree, and they interact with one another, alongside other mechanisms such...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
DEMENTIA symptoms include memory loss, difficulty concentrating, and having slower thoughts. But, you could lower your risk of developing Alzheimer's disease signs with this simple breakfast swap. Should you change the foods you eat to protect against dementia?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSION: We conclude that applying qEEG using the automated SPR method can be helpful in identifying patients with SCD and MCI that have a high risk of converting to dementia over a 5-year period. As the discriminant power of the method is of moderate degree, it should be used in addition to routine diagnostic methods. PMID: 32610316 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Authors: Maher PA Abstract Alzheimer's disease (AD) is the most common form of dementia with the numbers expected to increase dramatically as our society ages. There are no treatments to cure, prevent, or slow down the progression of the disease. Age is the single greatest risk factor for AD. However, to date, AD drug discovery efforts have generally not taken this fact into consideration. Multiple changes associated with brain aging, including neuroinflammation and oxidative stress, are important contributors to disease development and progression. Thus, due to the multifactorial nature of AD, the one target strat...
Source: The Yale Journal of Biology and Medicine - Category: Universities & Medical Training Tags: Yale J Biol Med Source Type: research
Alzheimer’s disease (AD) is the most prevalent form of dementia in the elderly population, representing a global public health priority. Despite a large improvement in understanding the pathogenesis of AD, the etiology of this disorder remains still unclear, and no current treatment is able to prevent, slow, or stop its progression. Thus, there is a keen interest in the identification and modification of the risk factors and novel molecular mechanisms associated with the development and progression of AD. In this context, it is worth noting that several findings support the existence of a direct link between neuronal...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Those with Crohn ’s disease or ulcerative colitis had higher rates of Alzheimer’s disease and other forms of dementia.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Alzheimer ' s Disease Dementia Digestive Tract Crohn Source Type: news
DEMENTIA has no cure but research suggests the choices you make in life may influence your risk of brain decline later on. To that end, certain dietary items have been shown to increase your risk of Alzheimer's disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Volicer L Abstract Alzheimer's disease is a major health problem all over the world. The role of beta-amyloid (Aβ) is at the center of investigations trying to discover the disease pathogenesis and to develop drugs for treatment or prevention on Alzheimer's disease. This review summarizes both physiological and pathological functions of Aβ and factors that may participate in the disease development. Known genetic factors are trisomy of chromosome 21, mutations of presenilin 1 and 2, and apolipoprotein E4. Lifetime stresses that increase the risk of development of Alzheimer's disease are described...
Source: The Chinese Journal of Physiology - Category: Physiology Tags: Chin J Physiol Source Type: research
DEMENTIA - the most common form of the condition, accounting for around 60 percent of diagnoses in the UK, is Alzheimer's disease. Here's the clue in your speech that may indicate you're suffering from this type of dementia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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