Sex and body mass index modify the association between leptin and sodium excretion: a cross-sectional study in an African population.

CONCLUSION: Leptin is associated positively with daytime and nighttime sodium excretion and lithium clearance suggesting a natriuretic rather than a sodium retaining effect of leptin. Sex and BMI are major confounders in this association. These results highlight the importance of sex and obesity in our understanding of the relationships between leptin, blood pressure and renal sodium handling. PMID: 31257412 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - Category: Cardiology Authors: Tags: Am J Hypertens Source Type: research