Combined loss of TFF3 and PTEN is associated with lethal outcome and overall survival in men with prostate cancer.

CONCLUSION: The study documents for the first time significant association for combined status of TFF3 expression and PTEN loss in OS and PCSM in patients not managed by surgical intervention. Prospective assessment of PTEN and TFF3 may provide further insight into molecularly subtyping PCa and aid in stratifying patients at risk for lethal disease. PMID: 31129769 [PubMed - indexed for MEDLINE]

https://www.ncbi.nlm.nih.gov/pubmed/31129769?dopt=Abstract

Source: Clinical Prostate Cancer - June 30, 2019 Category: Cancer & Oncology Authors: Abou-Ouf H, Ghosh S, Box A, Palanisamy N, Bismar TA Tags: J Cancer Res Clin Oncol Source Type: research