Risperidone treatment after transient ischemia induces hypothermia via 5-HT2aAntagonism and provides neuroprotection in the gerbil hippocampus by decreasing oxidative stress

Background: Compelling evidence from preclinical and clinical studies has shown that mild hypothermia is neuroprotective against ischemic stroke. We investigated neuroprotectiveeffect of post-risperidone (RIS) treatment against transient ischemic injury and its mechanisms in the gerbil brain.

Source: Resuscitation - June 26, 2019 Category: Emergency Medicine Authors: Hyun Joon Lim, Jun Hwi Cho, Joong Bum Moon, Chan Woo Park, Taek Geun Ohk, Myoung Cheol Shin, Ka Eul Kim, Yoon Soo Park, Joon Ha Park, Ji Hyun Ahn, Moo Ho Won Tags: AP163 Source Type: research