Unusual Appearance of Basaloid SCC in Tonsil: A Case Report

AbstractBasaloid squamous cell carcinoma (BSCC) is a variant of oral squamous cell carcinoma, is an aggressive, high grade variant and rare subtype of the head and neck SCC that less common in tonsils. Here, we are reporting a case of BSCC involving the tonsil with an extension on the cervical lymph node region.
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research

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Conclusions: FDG PETCT scans accurately detected subclinical recurrence in 8% of patients surveyed. The systematic use of FDG PETCT as a surveillance tool for detection of recurrence in asymptomatic patients with treated head and neck cancers should be further evaluated in larger trials.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Head and Neck Posters Source Type: research
Santosh K. Ghosh1*, Thomas S. McCormick1,2 and Aaron Weinberg1* 1Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States 2Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States Human beta-defensins (hBDs, −1, 2, 3) are a family of epithelial cell derived antimicrobial peptides (AMPs) that protect mucosal membranes from microbial challenges. In addition to their antimicrobial activities, they possess other functions; e.g., cell activation, proliferation, regulation of cytokine/chemokine production, migration, diffe...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Conclusions In the span of a very short time—less than a decade—robotic head and neck surgery has transformed the management of the head and neck cancer, and it seems clear that the future of treatment for these cancers lies in a multimodal approach in which TORS is likely to play an important role. Nevertheless, it is important to keep in mind that the current indications for TORS are limited and long-term data on the safety and oncological outcomes are needed to better understand the true role of TORS in treatment of head and neck cancer. Nonetheless, the emergence of ever more advanced robotic instruments i...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
We present the Adelaide experience with this system thus far. The Medrobotics Flex® system was introduced in Adelaide in January 2017. Patient demographics, pathology, indication for surgery and complications are prospectively recorded for all cases. The first 20 patients are presented in this case series. 11/20 underwent surgery for malignant disease. Of these nine were diagnosed with oropharyngeal squamous cell carcinoma (OPSCC). Histopathology revealed clear margins of primary tumour excision in 8/9 patients. There were no intraoperative complications. In terms of secondary complications, one patient undergoing tons...
Source: Journal of Robotic Surgery - Category: Surgery Source Type: research
Despite diagnostic efforts to locate a primary tumor, roughly 3 percent of patients presenting with metastatic squamous cell carcinoma (SCC) to the neck will have no identifiable primary site [1]. Patients who initially present with metastatic lymph node(s) usually undergo a diagnostic work-up that includes physical examination, diagnostic imaging, which may include PET/CT, as well as pan-endoscopy and biopsy of suspicious mucosal primary sites and palatine tonsillectomy. This historical approach may identify as many as 44% of primary tumors [2].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: With an optimized analgesia regime TORS for OPSCC can be performed with postoperative pain levels comparable to bilateral tonsillectomy in adults. PMID: 29741427 [PubMed - as supplied by publisher]
Source: Acta Oto-Laryngologica - Category: ENT & OMF Authors: Tags: Acta Otolaryngol Source Type: research
ConclusionIt is feasible and safe to use this novel, flexible, single‐arm robot in performing a transoral robotic radical tonsillectomy and retropharyngeal lymph node dissection.
Source: Head and Neck - Category: ENT & OMF Authors: Tags: OPERATIVE TECHNIQUES Source Type: research
The incidence of oropharyngeal squamous cell carcinoma (OPC) has increased significantly worldwide [1]. Trends in OPC are attributed to increasing oral exposure to human papillomavirus (HPV) infection [2]. Indeed, approximately 70% of OPCs in the United States are attributable to HPV [3]. HPV-positive OPC (HPV-OPC) are typically small tumors that arise within lymphoid-associated epithelial crypts of the palatine and lingual tonsils [4], rendering clinical and radiographic imaging difficult [5 –11].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research
Treatment TermsHead and Neck Cancer Overview Rob Vaughn found a lump on his neck that turned out to be cancer that had spread from somewhere else in his body. The trouble was, doctors couldn ’t find the original site of the cancer. That made his treatment decisions difficult -- until two Duke specialists offered him options, including the option for watchful waiting instead of extensive treatment. Hero Image20170914_robvaughn_neckcancer_083_herocrop.jpg Preview Image Content Blocks Header A Search for the Source of Cancer ContentVaughn, a Charlotte, NC, father of two, was 47 and in good health when he felt th...
Source: dukehealth.org: Duke Health News - Category: Consumer Health News Authors: Source Type: news
Head and neck lymphomas arise from lymph nodes as well as extranodal locations including, Waldeyer ring, the sinonasal tract, nasopharynx and salivary glands [1]. The oropharynx contains the palatine tonsils as well as the base of tongue (BOT), both of these locations are part of Waldeyer ’s ring and are comprised of lymphoid tissue [2]. B cells proliferate and mature at these locations, which represent the first contact point for exogenous antigens entering the aerodigestive tract [3]. Lymphomas are subdivided into Hodgkin’s lymphoma (HL) and Non-Hodgkin’s lymphoma (NHL), with extranodal NHL being the se...
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research
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