Superbug MRSA susceptible to existing antibiotics

Methicillin-resistantStaphylococcus aureus (MRSA) has become a serious problem, forcing doctors to turn to antibiotics other than penicillin or penicillin derivatives, or to different drug cocktails, which are often less effective in treating hospital and community based infections.
Source: Medical Research Council General News - Category: Research Source Type: news

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Publication date: Available online 20 July 2019Source: PeptidesAuthor(s): Nathalia Rodrigues de Almeida, Jonathan Catazaro, Maddeboina Krishnaiah, Yashpal Singh Chhonker, Daryl J Murry, Robert Powers, Martin Conda SheridanAbstractThe rapid emergence of resistant bacterial strains has made the search for new antibacterial agents an endeavor of paramount importance. Cationic antimicrobial peptides (AMPs) have the ability to kill resistant pathogens while diminishing the development of resistance. Citropin 1.1 (Cit 1.1) is an AMP effective against a broad range of pathogens. 20 analogues of Cit 1.1 were prepared to understand...
Source: Peptides - Category: Biochemistry Source Type: research
Publication date: Available online 18 July 2019Source: Journal of Microbiological MethodsAuthor(s): Ming-An Tsai, Pei-Chi Wang, Shiomi Yoshida, Akio Aono, Satoshi Mitarai, Takayuki Wada, Shih-Chu ChenAbstractMycobacterium marinum is a zoonotic pathogen that can cause dermatological infection mainly from contaminated water or fish. Some well-known genetically similar species and subspecies are M. lifrandii and M. pseudoshottsii from amphibians and fish in aquaculture, and M. ulcerans, a causative agent of a neglected tropical disease (NTD), Buruli ulcer. They are believed to survive in water as their major niche, which migh...
Source: Journal of Microbiological Methods - Category: Microbiology Source Type: research
ConclusionsThe sustained potent activity of telavancin against US S. aureus isolates (100% susceptible) and the high rates of MRSA and MDR MRSA in the USA support the continued use of telavancin to treat indicated serious infections caused by S. aureus.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionsIntensive reinforcement of infection control practices, strict cohorting of ex-utero transfers, universal surveillance on admission, and improvement in HH and environmental hygiene compliance were key to infection prevention and control measures, resulting in elimination of MRSA transmission in our neonatal unit.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Methicillin resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) represent a major clinical problem in Colombia. The aim of this study was to evaluate the risk factors associated with MRSA SSTI in Colombia.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSIONS Our findings reinforce the idea that MSSA and MRSA strains should be carefully monitored, owing to their high pathogenic potential.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Conclusion: Arbekacin can be considered as safe and effective alternative to vancomycin in the management of MRSA infections. PMID: 31313549 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
In the pediatric population, infections by methicillin-resistant Staphylococcus aureus (MRSA) are associated with significant morbidity and hospital costs. Vancomycin is a glycopeptide antibiotic, widely used for...
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Research article Source Type: research
Healthcare-associated infections (HAIs) continue to be an ongoing threat to patients. “Despite the best care, patients get infections,” Brian Gross, business lead, genomics for infectious disease at Philips, told MD+DI. Because they are “technically avoidable, there’s pressure on hospitals to drive their numbers down.” Healthcare system professionals have struggled with two main problems when trying to identify and act on infection risks, Gross explained. “The problem is two-fold. First, because of current tools, all...
Source: MDDI - Category: Medical Devices Authors: Tags: Software Source Type: news
Publication date: Available online 16 July 2019Source: American Journal of Infection ControlAuthor(s): Shanice Cheatham, Dipendra Thapaliya, Mohammed Taha, Katherine Milliken, Mark R. Dalman, Jhalka Kadariya, Dylan Grenier, Tara C. SmithBackgroundMethicillin-resistant Staphylococcus aureus (MRSA) is common in medical institutions. We sought to examine the prevalence of S aureus on environmental surfaces in nursing homes and to obtain molecular information on contaminating strains.MethodsA total of 259 environmental samples were collected from 7 different nursing homes in Northeast Ohio (NEO), from suburban, urban, and rura...
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
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