DEPTOR induces a partial epithelial-to-mesenchymal transition and metastasis via autocrine TGF β1 signaling and is associated with poor prognosis in hepatocellular carcinoma

DEPTOR is an endogenous inhibitor of mTORC1 and mTORC2 that plays a vital role in the progression of human malignances. However, the biological function of DEPTOR in HCC metastasis and the underlying molecular...

Source: Journal of Experimental and Clinical Cancer Research - June 22, 2019 Category: Cancer & Oncology Authors: Jin Chen, Haidan Zhu, Qiumeng Liu, Deng Ning, Zhaoqi Zhang, Long Zhang, Jie Mo, Pengcheng Du, Xu Liu, Shasha Song, Yawei Fan, Huifang Liang, Jikui Liu, Bixiang Zhang and Xiaoping Chen Tags: Research Source Type: research