Risk factors for relapse and long-term outcome of idiopathic retroperitoneal fibrosis

ConclusionsSmoking habit, AKI at diagnosis, ANA positivity and lumbar pain were associated with relapse of RF after initial remission due to steroid and/or TMX therapy; the combination of these conditions was also predictive of worse renal function outcome. Identification of risk factors for relapse can be useful not only to modulate the choice, the dosage of first-line treatment and the duration of maintenance therapy but also for preventing a progressive loss of kidney function, as well.

Source: Clinical and Experimental Nephrology - June 21, 2019 Category: Urology & Nephrology Source Type: research