Persistently Upregulated Hippocampal mTOR Signals Mediated by Fecal SCFAs Impair Memory in Male Pups with SMM Exposure in Utero.
CONCLUSION: In utero exposure to SMM, persistent upregulation of the hippocampal mTOR pathway related to dysfunction of the gut (SCFA)-brain axis may contribute to cognitive deficits in male offspring.
PMID: 31217051 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - Category: Biomedical Science Authors: Zhu YT, Liu XJ, Liu KY, Zhang Q, Yang LS, Wei R, Zhang JJ, Tao FB Tags: Biomed Environ Sci Source Type: research