Calcitriol protects the Blood-Brain Barrier integrity against ischemic stroke and reduces vasogenic brain edema via antioxidant and antiapoptotic actions in rats.

CONCLUSION: Calcitriol may reduce brain injury and attenuate vasogenic edema by upregulating antioxidant enzymes activities, reducing cell apoptosis and increasing BDNF protein in the brain tissue in a rat model of ischemic stroke. PMID: 31220552 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31220552?dopt=Abstract

Source: Brain Research Bulletin - June 16, 2019 Category: Neurology Authors: Sadeghian N, Shadman J, Moradi A, Ghasem Golmohammadi M, Panahpour H Tags: Brain Res Bull Source Type: research