Gastric carcinoma: stage migration by immunohistochemically detected lymph node micrometastases

Conclusion Immunohistostaining of regional lymph nodes in node-negative gastric carcinoma patients leads to an increased detection of micrometastases with significant implications for the staging system. Although no impact on survival time was shown, the higher recurrence rate for node-positive patients younger than 70 years indicates a prognostic value of immunohistochemically detectable micrometastases.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research