Homozygosity mapping of autosomal recessive intellectual disability loci in 11 consanguineous Pakistani families.

CONCLUSION: The homozygous loci identified in this study might harbour candidate genes for ID in these studied families. Therefore, we are proceeding with next-generation sequencing analysis of the families, using whole-exome approaches, and anticipate that this will identify the causative gene/mutation within the identified HBD regions for many of the families studied here. PMID: 25434728 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25434728?dopt=Abstract

Source: Acta Neuropsychiatrica - December 6, 2014 Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research