In vivo antiplasmodial potential of three herbal methanolic extracts in mice infected with Plasmodium berghei NK65

ConclusionsOverall results revealed that herbal plants may be active in the development of novel and cheap antimalarial compounds.
Source: Chinese Herbal Medicines - Category: Complementary Medicine Source Type: research

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We report a case of severe babesiosis caused by the bovine pathogen Babesia divergens with the development of multisystem failure in a splenic host. Immunosuppression other than splenectomy can also predispose people to B. divergens. There was heavy multiple invasion of up to 14 parasites inside the erythrocyte, which had not been previously observed even in asplenic hosts. The factors preventing the effectiveness of the vector Ixodes ricinus in the transmission of the organisms to humans are discussed.
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 15 July 2019Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Cora Delling, Denny Böttcher, Vivien Schiffbauer, Andreas Bernhard, Ronald SchmäschkeAbstractThe cestode Taenia crassiceps parasitizes in the intestine of domestic and wild carnivores, especially in red foxes. Usually, the metacestode stage, also known as Cysticercus longicollis, is located in muscles, peritoneal and pleural cavity of wild rodents. In this case, larval stages were found in a female Cape fur seal, which lived in a German zoo since June 1998. In January 2019, the animal pr...
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
Endoparasitoid wasps which lay eggs inside the bodies of other insects use various strategies to protect their offspring from the host immune response. The hymenopteran species of the genus Leptopilina, parasites of Drosophila, rely on injection of a venom which contains proteins and peculiar vesicles (hereafter venosomes). We show here that the injection of purified L. boulardi venosomes is sufficient to impair the function of the Drosophila melanogaster lamellocytes, a hemocyte type specialized in the defense against wasp eggs, and thus the parasitic success of the wasp. These venosomes seems to have a unique extracellul...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
The number of biting Asian tiger mosquitoes, which spread dengue and Chikungunya, has been reduced by more than 80 per cent at two sites in Guangzhou, China
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Authors: Yoo Jung L, Lee YH, Chung DH, Shin JW PMID: 31303087 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
A concept to mitigate parasitic lasing in mid-IR fiber amplifiers using a single long period fiber grating is shown. Using tightly confined ultrashort laser pulses at 800 nm, a grating was directly inscribed into the core of an erbium doped fluoride glass fiber showing a strong attenuation down to ...
Source: Optics Express - Category: Physics Authors: Source Type: research
DNA transformation of parasitic nematodes enables novel approaches to validating predictions from genomic and transcriptomic studies of these important pathogens. Notably, proof of principle for CRISPR/Cas9 mutagenesis has been achieved in Strongyloides spp. allowing identification of molecules essential to the functions of sensory neurons that mediate behaviors comprising host finding, invasion and location of predilection sites by parasitic nematodes. Likewise, CRISPR/Cas9 knockout of the developmental regulatory transcription factor Ss-daf-16 has validated its function in regulating morphogenesis of infective third-stag...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
ConclusionsThe high frequency ofL.braziliensis infection in dogs with ulcers and the similarities between the isolates ofL.braziliensis and cutaneous leishmaniasis in dogs and humans in an endemic area of TL, raise the possibility of an important role of dogs in the transmission chain ofL.braziliensis.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Novel parasites can have wide-ranging impacts, not only on host populations, but also on the resident parasite community. Historically, impacts of novel parasites have been assessed by examining pairwise interactions between parasite species. However, parasite communities are complex networks of interacting species. Here we used multivariate taxonomic and trait-based approaches...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
AbstractTwo studies at the National Animal Production Research Institute (NAPRI), Zaria, Nigeria, compared Red Sokoto (RS), Sahelian (SG), and West African Dwarf (WAD) goats after experimental or natural infection withHaemonchus contortus. In the first study, 20 RS, 17 SG, and 14 WAD kids were challenged at 6  months of age with 5000 L3 larvae ofH. contortus. Fecal egg counts (FEC), packed cell volumes (PCV), and body weights (BW) were recorded 0, 28, 35, and 42  days after infection. The FEC and PCV were affected only by time of measurement. In the second study, 322 RS and 97 SG kids were produced at NAPRI over ...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
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