Investigation of new candidate genes in retinoblastoma using the TruSight One “clinical exome” gene panel

ConclusionThis study might be an important report on emphazing the mutational status of other genes in patients withoutRB1 gene mutations and having high risk for developing Rb. The study also indicates the interaction between the retinoic acid pathway and Rb oncogenesis for the first time.

Source: Molecular Genetics & Genomic Medicine - June 16, 2019 Category: Genetics & Stem Cells Authors: Demet Akdeniz, Seref Bugra Tuncer, Rejin Kebudi, Betul Celik, Gozde Kuru, Seda Kilic, Ozge Sukruoglu Erdogan, Mukaddes Avsar, Sema Buyukkapu Bay, Samuray Tuncer, Hulya Yazici Tags: ORIGINAL ARTICLE Source Type: research