Coding Region Mutation Screening in Optineurin in Chinese Normal-Tension Glaucoma Patients.

Conclusions: This study confirmed the association of the OPTN T34T variant with NTG, suggesting that OPTN is a susceptibility gene for NTG in Chinese. Moreover, a variant with amino acid change (I407T) was identified in NTG but not in controls. Further studies are warranted to assess whether this variant is a causative mutation for NTG. PMID: 31198474 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31198474?dopt=Abstract

Source: Disease Markers - June 15, 2019 Category: Laboratory Medicine Tags: Dis Markers Source Type: research