USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma

Conclusion: Our findings reveal that USP5 serve as a potential target for tumor intervention and provide a preliminary antitumor therapy for inhibit EMT by targeting USP5 or its interaction with SLUG in HCC.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Jing Meng, Xiaoyu Ai, Yueyang Lei, Weilong Zhong, Baoxin Qian, Kailiang Qiao, Xiaorui Wang, Bijiao Zhou, Hongzhi Wang, Longcong Huai, Xiaoyun Zhang, Jingxia Han, Yinyin Xue, Yuan Liang, Honggang Zhou, Shuang Chen, Tao Sun, Cheng Yang Tags: Research Paper Source Type: research