Controllable Autocatalytic Cleavage-Mediated Fluorescence Recovery for Homogeneous Sensing of Alkyladenine DNA Glycosylase from Human Cancer Cells

Conclusion: The proposed strategy can provide a facile and universal platform for the monitoring of DNA damage-related repair enzymes, holding great potential for DNA repair-related biochemical research, clinical diagnosis, drug discovery, and cancer therapy.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Li-Juan Wang, Ming-Li Luo, Xiao-Yun Yang, Xiao-Fang Li, Yanxia Wu, Chun-Yang Zhang Tags: Research Paper Source Type: research