Perineural and lymphovascular invasion predicts for poor prognosis in locally advanced rectal cancer after neoadjuvant chemoradiotherapy and surgery

Conclusion: For patients with LARC undergoing nCRT and surgery, PNI-positive and/or LVI positive were associated with poorer DFS and OS. And PNI-positive, rather than LVI-positive, may benefit from adjuvant chemotherapy.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Quanquan Sun, Tongxin Liu, Peng Liu, Jialin Luo, Na Zhang, Ke Lu, Haixing Ju, Yuping Zhu, Wei Wu, Lingnan Zhang, Yongtian Fan, Yong Liu, Dechuan Li, Yuan Zhu, Luying Liu Tags: Research Paper Source Type: research