Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.

CONCLUSION: These results revealed that icariin might potentially be useful as an adjuvant agent in cancer chemotherapy to enhance the effect of tamoxifen through suppression of autophagy in vitro and provide insight into the therapeutic potential of icariin for the treatment of chemo-resistant breast cancer.
PMID: 31172425 [PubMed - as supplied by publisher]

Source: Breast Cancer - June 5, 2019 Category: Cancer & Oncology Authors: Cheng X, Tan S, Duan F, Yuan Q, Li Q, Deng G Tags: Breast Cancer Source Type: research