Dopamine D 1 and D 2 receptors mediate analgesic and hypnotic effects of l -tetrahydropalmatine in a mouse neuropathic pain model

ConclusionsThese findings indicated thatl-THP exerted analgesic effects by agonism D1R and antagonism D2R, and the antagonism of D2R mediated the hypnotic effect ofl-THP in PSNL mice.

Source: Psychopharmacology - June 5, 2019 Category: Psychiatry Source Type: research