Emerging roles for Interleukin-11 in disease.

Emerging roles for Interleukin-11 in disease. Growth Factors. 2019 Jun 04;:1-11 Authors: Nguyen PM, Abdirahman SM, Putoczki TL Abstract Interleukin (IL)-11 belongs to the IL-6 family of cytokines, discovered over 30 years ago. While early studies focused on the ability of IL-11 to stimulate megakaryocytopoiesis, the importance of this cytokine to inflammatory disease and cancers is only just beginning to be uncovered. This review outlines recent advances in our understanding of IL-11 biology, and highlights the development of novel therapeutics with the potential for clinical targeting of signaling by this cytokine in multiple diseases. PMID: 31161823 [PubMed - as supplied by publisher]
Source: Growth Factors - Category: Research Tags: Growth Factors Source Type: research