Predominant detection of the subgroup A2b human metapneumovirus strain with 111-nucleotide duplication in Yokohama City, Japan in 2018.

Predominant detection of the subgroup A2b human metapneumovirus strain with 111-nucleotide duplication in Yokohama City, Japan in 2018.
Jpn J Infect Dis. 2019 May 31;:
Authors: Saikusa M, Nao N, Kawakami C, Usuku S, Tanaka N, Tahara M, Takeda M, Okubo I
Abstract
  Human metapneumovirus (HMPV) has been a major causative agent of acute respiratory infections in humans. Recently two types of variant A2b subtype HMPV strains possessing 111- or 180-nucleotide duplication (nt-dup) in the G gene (HMPV A2b180nt-dup and HMPVA2b111nt-dup, respectively) were detected in Japan, Spain, Vietnam, and China. Surveillance for infectious agents in Yokohama City, Japan revealed that the HMPV111nt-dup strain became predominant in Yokohama City in 2018. In contrast, no classical HMPV A2b strain was detected after 2017. These data suggest a beneficial role of the 111nt-dup in the G gene for the transmission of HMPV.
PMID: 31155603 [PubMed - as supplied by publisher]

Source: Japanese Journal of Infectious Diseases - May 30, 2019 Category: Infectious Diseases Authors: Saikusa M, Nao N, Kawakami C, Usuku S, Tanaka N, Tahara M, Takeda M, Okubo I Tags: Jpn J Infect Dis Source Type: research