CD146-targeted, Multimodal Image-guided Photoimmunotherapy of Melanoma

Conclusion: We demonstrated that 89Zr-Df-YY146 and IR700-YY146 are a promising theranostic pair with the former revealing CD146 expression in melanoma as a PET probe and the latter specifically treating CD146-positive melanoma as an effective PIT agent.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Wei, W., Jiang, D., Ehlerding, E., Engle, J., Luo, Q.-Y., Cai, W. Tags: Center for Molecular Imaging Innovation & amp; Translation (CMIIT) YIA Symposium Source Type: research