K-ras-ERK1/2 down-regulates H2A.XY142ph through WSTF to promote the progress of gastric cancer

Histone H2AX phosphorylation at the site of Tyr-142 can participates in multiple biological progressions, which is including DNA repair. Ras pathway is closely involved in human cancers. Our study investigated...

Source: BMC Cancer - May 31, 2019 Category: Cancer & Oncology Authors: Chao Dong, Jing Sun, Sha Ma and Guoying Zhang Tags: Research article Source Type: research