Electrochemical, biodegradation and cytotoxicity of graphene oxide nanoparticles/polythreonine as a novel nano-coating on AZ91E Mg alloy staple in gastrectomy surgery

Publication date: October 2019Source: Materials Science and Engineering: C, Volume 103Author(s): Renad S. El-Kamel, Azza A. Ghoneim, Amany M. FekryAbstractGraphene oxide nanoparticles/polythreonine polymer as a nano-coating on AZ91E Mg alloy was considered as a new temporary implant for gastrectomy applications. This coating as a novel one is decomposable and has bio-viability possessions. Various electrochemical measurements were utilized for corrosion performance estimation of Mg alloy in peritoneal fluid with time of dipping. It was recognized that the nano-coating is fixed for 20 days giving unexpected high corrosion resistance. All experimental outcomes were verified by scanning electron microscope (SEM) and Energy dispersive X-ray (EDX) techniques. Moreover, in vitro antibacterial, and cytotoxicity of metal with and/or without coating utilizing MTT assay for cell viability analysis were achieved.
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research