Prevalence and Predictors of Benzodiazepine Monotherapy in Patients With Depression: A National Cross-Sectional Study.

CONCLUSIONS: Benzodiazepine monotherapy is utilized in nearly 1 in 10 patients treated for depression. Adults aged 45 to 65 years, patients prescribed opioids, patients seen by primary care providers, and those with underlying anxiety, epilepsy, or pulmonary disorders are at highest risk. PMID: 31120203 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Related Links:

Publication date: Available online 19 June 2019Source: Physiology &BehaviorAuthor(s): Celio Estanislau, André W.N. Veloso, Guilherme B. Filgueiras, Taimon P. Maio, Maria L.C. Dal-Cól, Daniel C. Cunha, Rodrigo Klein, Lucas F. Carmona, Alberto Fernández-TeruelAbstractRodent self-grooming is a behavior that, besides its cleaning function, can be led by arousing experiences. A putative trait-like nature of this behavior was studied. With the aim of providing information about how grooming behavior can reflect different behavioral processes, an individual differences approach was adopted. Fifty nine mal...
Source: Physiology and Behavior - Category: Physiology Source Type: research
Authors: Bor-Seng-Shu E, Paschoal FM, Almeida KJ, De Lima Oliveira M, Nogueira RC, Teixeira MJ, Walter U Abstract Substantia nigra (SN) hyperechogenicity has been proved to be a characteristic finding for idiopathic Parkinson's disease (PD), occurring in more than 90% of the patients. This echofeature is owed to increased amounts of iron in the SN region and reflects a functional impairment of the nigrostriatal dopaminergic system. In a prospective blinded study in which a group of patients with early mild signs and symptoms of unclear Parkinsonism were followed until a definite clinical diagnosis of PD, the hypere...
Source: Journal of Neurosurgical Sciences - Category: Neurosurgery Tags: J Neurosurg Sci Source Type: research
Authors: Jenabi E, Bashirian S, Khazaei S, Basiri Z Abstract This meta-analysis evaluated the association between maternal pre-pregnancy body mass index (BMI) and the risk of attention deficit hyperactivity disorder (ADHD) among children and adolescents. The search strategy was conducted until December 2018 in databases of PubMed, Web of Science and Scopus. The ORs or HRs with 95% confidence intervals (CI) extracted from eligible studies used as the common measure of association among studies. A significant association was found between overweight women and risk of ADHD among children with the pooled estimates of H...
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Publication date: Available online 18 June 2019Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Qian Wei, Liuyang Dong, Fen Jiao, Wenqing QinAbstractCalcite, as a gangue mineral, needs to be removed from the target minerals in the flotation. Single depressant citric acid (CA) or Fe (III) species has a limited depressive effect on calcite in the sodium oleate (NaOL) flotation system. In this paper, the floatability of calcite with single depressant (CA or Fe (III)) and mixed depressant (CA /Fe (III)) was studied by microflotation experiments. Solution chemical calculation and X-ray photoele...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
ConclusionAcute organophosphate poisoning treated with atropine showed a potential for inducing prothrombotic coagulation abnormalities, presented with PT. This life-threatening complication may additionally contribute to prolonged morbidity and mortality in OP poisonings, especially in patients with medical history of comorbidites.
Source: Toxicology Reports - Category: Toxicology Source Type: research
Publication date: Available online 18 June 2019Source: Reproductive BioMedicine OnlineAuthor(s): Alessandra Parrella, Mohamad Irani, Derek Keating, Stephen Chow, Zev Rosenwaks, Gianpiero D. PalermoAbstractResearch QuestionAlthough ooplasmic maturity has been studied for some time, it remains poorly defined. We aim to identify the competence of MII oocytes in terms of fertilization and embryo development while considering the proportional maturity of the retrieved cohort.DesignCouples treated by ICSI between 1993 and 2017 comprising female partners ≤35 years old were included. Cycles were divided into four groups accordi...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
In this study, miRNome profiling suggested differential expression of 163 miRNAs (of 887 miRNAs detected) in the kidneys from pregnant mice at 6.5 days gestation when compared to non-pregnant female mice, of which 35 and 128 miRNAs were potentially down- and up-regulated, respectively. We performed network and pathway analyses of the>1700 potential mRNA targets of the differentially expressed miRNAs using MiRNet, Gene Ontology, Reactome and KEGG analyses. The mRNA targets were over-represented in numerous cellular signalling pathways, including cellular protective responses. In addition, we explored 13 and 29 potentia...
Source: Molecular Genetics and Metabolism Reports - Category: Genetics & Stem Cells Source Type: research
We described the evolution HGA excretion and tyrosine evolution in 3 AKU patients treated by very low dosage of nitisinone with regards to their daily protein intakes. We also described the first pregnancy in an AKU patient treated by nitisinone.ResultsWe found mild clinical signs of alkaptonuria on vertebra MRI in two young adults and homogentisate deposition in teeth of a 5 years old girl. Very low dose of nitisinone (10% of present recommended dose: 0.2 mg/day) allowed to decrease homogentisic acid by>90% without increasing tyrosine levels above 500 μmol/ in these three patients.InterpretationsThe analysis o...
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
Conclusions: Fasting and postprandial plasma glucose screening can replace gestational diabetes mellitus screening in women who refuse to have the glucose load test. PMID: 31210349 [PubMed - in process]
Source: Eastern Mediterranean Health Journal - Category: Middle East Health Tags: East Mediterr Health J Source Type: research
In this study, we compared the dynamic resting-state local and large-scale FC between PTSD patients (n = 22) and healthy controls (HC; n = 22; conducted as standard deviation in resting-state local and large-scale FC over a series of sliding windows). Local dynamic FC was examined by calculating the dynamic regional homogeneity (dReHo), and large-scale dynamic FC (dFC) was investigated between regions with significant dReHo group differences. For the PTSD patients, we also investigated the relationship between symptom severity and dFC/dReHo. Our results showed that PTSD patients were characterized by I) increased dynamic (...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
More News: Anxiety | Bipolar | Depression | Epilepsy | Mania | Pregnancy | Primary Care | Psychiatry | Study