Conditioning pain modulation reduces pain only during the first stimulation of the temporal summation of pain paradigm in healthy participants
ConclusionsThe current study indicates that mild to severe stimuli administered by cuff algometry does not modulate summation effect of temporal summation of pain, which could indicate that pain facilitatory mechanisms are more potent compared with pain inhibitory mechanisms.SignificanceCurrent knowledge on the interaction effect of pro and anti ‐nociceptive paradigms are the lacking. The current study indicates that conditioning pain modulation does not modulate the summation effect of temporal summation of pain, when evaluated by computerized pressure algometry. This finding was independent of the mild, moderate and severe painful cond itioning intensities.
Source: European Journal of Pain - Category: Anesthesiology Authors: Sinead Holden,
Kristian Kj ær Petersen,
Lars Arendt‐Nielsen,
Thomas Graven‐Nielsen Tags: ORIGINAL MANUSCRIPT Source Type: research