Spontaneous cerebrospinal fluid rhinorrhoea and aspiration pneumonitis following initiation of continuous positive airway pressure treatment for obstructive sleep apnoea

In this report, we describe a 53 ‐year‐old woman with severe OSA who, while being evaluated for possible intracranial hypertension, developed spontaneous CSF rhinorrhoea and CSF aspiration pneumonitis as a complication of CPAP therapy. Magnetic resonance imaging confirmed fluid tracks at the skull base, and a nasal swab demonst rated positive β2‐transferrin. Computer tomography (CT) chest showed findings consistent with CSF aspiration pneumonitis. Resolution of both CSF leak and pneumonitis were noted following treatment with azetozolamide and curative endoscopic trans‐nasal surgery along with ventriculoperitoneal shu nt.

Source: Respirology Case Reports - May 19, 2019 Category: Respiratory Medicine Authors: Sanjiwika Lalanjani Wasgewatta, Nathan Manning, Michael Redmond, Diane Howard, Subash Shanthakumar Heraganahally Tags: Case Report Source Type: research