Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer

The TG-interacting factor 1 (TGIF1) gene, which encodes a nuclear transcriptional corepressor of the TGF β1/Smad signaling pathway, has been implicated in the pathogenesis of various types of human cancer; howe...

Source: Molecular Cancer - May 20, 2019 Category: Cancer & Oncology Authors: Ching-Chieh Weng, Mei-Jen Hsieh, Chia-Chen Wu, Yu-Chun Lin, Yan-Shen Shan, Wen-Chun Hung, Li-Tzong Chen and Kuang-Hung Cheng Tags: Research Source Type: research